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補(bǔ)體組分1q子成分樣蛋白1抗體
  • 產(chǎn)品貨號(hào)：
    BN40281R
  • 中文名稱：
    補(bǔ)體組分1q子成分樣蛋白1抗體
  • 英文名稱：
    Rabbit anti-C1QL1 Polyclonal antibody
  • 品牌：
    Biorigin

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    產(chǎn)品規(guī)格

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  • BN40281R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Mouse,Rat(predicted:Human,Dog,Pig,Cow) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40281R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Mouse,Rat(predicted:Human,Dog,Pig,Cow) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱C1QL1
中文名稱補(bǔ)體組分1q子成分樣蛋白1抗體
別    名C1q related factor; C1q-related factor; C1ql1; C1QRF; C1QRF_HUMAN; C1QTNF14; Complement component 1 Q subcomponent like 1; Complement component 1 Q subcomponent-like 1; CRF; Gliacolin.  
研究領(lǐng)域神經(jīng)生物學(xué)  細(xì)胞粘附分子  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量25kDa
細(xì)胞定位分泌型蛋白 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human C1QL1:21-120/258 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹C1q is part of the C1 enzyme complex, which activates the serum complement system. The residues of the globular domain in C1q share homology with several other secreted and membrane-bound collagen or collagen-like proteins, including pre-cerebellin and collagen types VIII and X, as well as the human and mouse genes encoding Apm1/BPB80 and AdipoQ/ACRP30, respectively. These various C1q-related proteins are found in adipose serum, corneal endothelium, chondrocytes and cerebral Purkinje cells. C1qL1 (complement component 1, q subcomponent-like 1), also known as CRF or C1QRF, is a polypeptide with a hydrophobic signal sequence, a collagenous region and a globular domain at the carboxy terminus, which shares homology to the C1q globular domain. C1qL1 transcripts are most abundant in areas of the nervous system that are associated with motor function, including cerebral Purkinje cells, the pons, the accessory olivary nucleus, and the red nucleus. The similarity of mouse C1qL1 to human C1qL1 suggests a conserved and important role for the protein. In humans, the gene encoding C1qL1 maps to chromosome 17q21.

Function:
May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity).

Subunit:
Interacts with BAI3 (By similarity).

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed in brainstem.

Similarity:
Contains 1 C1q domain.
Contains 1 collagen-like domain.

SWISS:
O75973

Gene ID:
10882

Database links:

Entrez Gene: 10882 Human

Omim: 611586 Human

SwissProt: O75973 Human

Unigene: 134012 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.