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核轉(zhuǎn)錄因子SOX8抗體
  • 產(chǎn)品貨號：
    BN40316R
  • 中文名稱：
    核轉(zhuǎn)錄因子SOX8抗體
  • 英文名稱：
    Rabbit anti-SOX8 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN40316R-100ul

    100ul

    ￥2360.00

    交叉反應：Mouse(predicted:Human,Rat,Cow,Horse) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40316R-200ul

    200ul

    ￥3490.00

    交叉反應：Mouse(predicted:Human,Rat,Cow,Horse) 推薦應用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱SOX8
中文名稱核轉(zhuǎn)錄因子SOX8抗體
別    名SOX 8; Sox8; SOX8_HUMAN; SRY (sex determining region Y) box 8; SRY box 8; SRY box containing gene 8; Transcription factor SOX 8; Transcription factor SOX-8; Transcription factor SOX8.  
研究領域神經(jīng)生物學  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Mouse,  (predicted: Human, Rat, Cow, Horse, )
產(chǎn)品應用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量47kDa
細胞定位細胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SOX8:101-200/446 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Function:
May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.

Subcellular Location:
Nucleus.

Tissue Specificity:
Contains 1 HMG box DNA-binding domain.

Similarity:
Contains 1 HMG box DNA-binding domain.

SWISS:
P57073

Gene ID:
30812

Database links:

Entrez Gene: 30812 Human

Entrez Gene: 20681 Mouse

Entrez Gene: 302993 Rat

Omim: 605923 Human

SwissProt: P57073 Human

SwissProt: Q04886 Mouse

Unigene: 243678 Human

Unigene: 258220 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications















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