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B7H6蛋白抗體
  • 產(chǎn)品貨號(hào)：
    BN40374R
  • 中文名稱：
    B7H6蛋白抗體
  • 英文名稱：
    Rabbit anti-B7-H6 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號(hào)

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  • BN40374R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40374R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA

產(chǎn)品描述

英文名稱B7-H6
中文名稱B7H6蛋白抗體
別    名B7 homolog 6; B7-H6; B7H6; B7H6_HUMAN; DKFZp686O24166; Natural cytotoxicity triggering receptor 3 ligand 1; NCR3LG1; Putative Ig like domain containing protein DKFZp686O24166/DKFZp686I21167.  
研究領(lǐng)域細(xì)胞生物  免疫學(xué)  染色質(zhì)和核信號(hào)  
抗體來(lái)源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse, 
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量48kDa
細(xì)胞定位細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human B7-H6:51-150/454 <Extracellular>
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011].

Function:
Triggers NCR3-dependent natural killer cell activation.

Subunit:
Monomer. Interacts specifically with NCR3, but not with other natural killer cell-activating receptors, including NCR1, NCR2 and KLRK1.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Tissue Specificity:
Not detected in any normal tissue tested. Expressed at the surface of several tumor cell lines including T and B lymphomas, myeloid leukemias, melanomas, carcinomas and large T SV40 antigen-transformed cells (at protein level).

Similarity:
Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:
Q68D85

Gene ID:
374383

Database links:

Entrez Gene: 374383 Human

Omim: 613714 Human

SwissProt: Q68D85 Human

Unigene: 146274 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.