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希佩爾-林道結合蛋白抗體
  • 產(chǎn)品貨號：
    BN40381R
  • 中文名稱：
    希佩爾-林道結合蛋白抗體
  • 英文名稱：
    Rabbit anti-PFDN3 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產(chǎn)品規(guī)格

    售價

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  • BN40381R-100ul

    100ul

    ￥2360.00

    交叉反應：Human,Mouse 推薦應用：WB,IHC-P,IHC-F,ICC,IF

  • BN40381R-200ul

    200ul

    ￥3490.00

    交叉反應：Human,Mouse 推薦應用：WB,IHC-P,IHC-F,ICC,IF

產(chǎn)品描述

英文名稱PFDN3
中文名稱希佩爾-林道結合蛋白抗體
別    名HIBBJ 46; HIBBJ46; PFD 3; PFD3; PFD3_HUMAN; PFDN 3; Prefoldin 3; Prefoldin subunit 3; Prefoldin3; VBP 1; VBP-1; VBP1; VHL binding protein 1; VHL-binding protein 1; Von Hippel Lindau binding protein 1; Von Hippel-Lindau-binding protein 1.  
研究領域細胞生物  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  結合蛋白  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應Human, Mouse, 
產(chǎn)品應用WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量23kDa
細胞定位細胞核 細胞漿 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human PFDN3:51-150/197 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The protein encoded by this gene interacts with the Von Hippel-Lindau protein to form an intracellular complex. The encoded protein functions as a chaperone protein, and may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm. Alternative splicing and the use of alternate transcription start sites results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Jan 2015]

Function:
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

Subcellular Location:
Cytoplasm. Nucleus. In complex with VHL can translocate to the nucleus.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the prefoldin subunit alpha family.

SWISS:
P61758

Gene ID:
7411

Database links:

Entrez Gene: 508727 Cow

Entrez Gene: 481089 Dog

Entrez Gene: 7411 Human

Entrez Gene: 22327 Mouse

Omim: 300133 Human

SwissProt: Q2TBX2 Cow

SwissProt: P61758 Human

SwissProt: P61759 Mouse

Unigene: 436803 Human

Unigene: 8294 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.