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叉頭蛋白F2抗體
  • 產(chǎn)品貨號(hào)：
    BN40413R
  • 中文名稱：
    叉頭蛋白F2抗體
  • 英文名稱：
    Rabbit anti-FOXF2 Polyclonal antibody
  • 品牌：
    Biorigin

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  • BN40413R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Mouse(predicted:Human,Rat,Chicken) 推薦應(yīng)用：WB,ELISA

  • BN40413R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Mouse(predicted:Human,Rat,Chicken) 推薦應(yīng)用：WB,ELISA

產(chǎn)品描述

英文名稱FOXF2
中文名稱叉頭蛋白F2抗體
別    名FKH L6; FKHL 6; FKHL6; Forkhead box F2; Forkhead box protein F2; Forkhead like 6; Forkhead related activator 2; Forkhead related protein FKHL6; Forkhead related transcription factor 2; FOX F2; FOXF 2; FREAC 2; FREAC2; OTTHUMP00000017863;   
研究領(lǐng)域腫瘤  細(xì)胞生物  發(fā)育生物學(xué)  神經(jīng)生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Mouse,  (predicted: Human, Rat, Chicken, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量46kDa
細(xì)胞定位細(xì)胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human FOXF2:65-160/444 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. FOXF2 (forkhead box F2), also known as FKHL or FREAC2, is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. FOXF2 interacts with transcription factors TFIIB and TBP, and may be involved in regulating transcription in embryogenesis and pattern formation in multicellular organisms. FOXF2-deficient mice develop cleft palate and an abnormal tongue, which suggests that FOXF2 may be critical for palatogenesis.

Function:
FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes.

Subunit:
Interacts with the transcription factors TBP and TFIIB.

Subcellular Location:
Nuclear.

Similarity:
Contains 1 fork-head DNA-binding domain.

SWISS:
Q12947

Gene ID:
2295

Database links:

Entrez Gene: 2295 Human

Entrez Gene: 14238 Mouse

Omim: 603250 Human

SwissProt: Q12947 Human

SwissProt: O54743 Mouse

Unigene: 484423 Human

Unigene: 125548 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.